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14-3-3 Monoclonal Antibody

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Product Description

Product Name Cat# Clone# Isotype Applications Reactivity Unit/Size
14-3-3 Monoclonal Antibody E-AB-27413 954 IgG1 WB,IHC,IF,ELISA* Human,Rat60μL, 120μL, 200μL


14-3-3 proteins interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma,epsilon,beta,zeta,sigma,theta,tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain,and have been implicated in several neurodegenerative diseases,including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody recognizes 14-3-3 tau (YWHAQ),eta (YWHAH),and zeta (YWHAZ),but not epsilon (YWHAE).

Spec Sheet E-AB-27413 (PDF File)

Synonyms 14 3 3,14 3 3 protein T cell,14 3 3 protein tau,14 3 3 protein theta,14-3-3 tau,HS1,Protein HS1,YWHAQ
Swiss-Prot P27348
Concentration 1 mg/mL
Host Mouse
Immunogen Fusion protein of 14-3-3
Purification Method Protein G purification
Formulation PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Storage Store at -20?. Avoid freeze / thaw cycles.
Dilution WB 1:500-1:5000, IHC 1:50-1:500, IF 1:20-1:200

Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .


* Remark Icon :

WB=Western Blotting, IP=Immunoprecipitation, IF=Immunofluorescence, IHC=Immunohistochemistory, IHC-p=Immunohistochemistory Paraffin, FCM=Flow Cytometry, CH=ChIP Assay

Manufactured by: Elabscience

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