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4EBP1 Monoclonal Antibody

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Product Description

Product Name Cat# Clone# Isotype Applications Reactivity Unit/Size
4EBP1 Monoclonal Antibody E-AB-27001 133 IgG2b WB,IHC,IF,ELISA* Human,Mouse,Rat60μL, 120μL, 200μL


Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1),is a member of 4EBPs family,which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E,thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors,hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1,alpha,beta and gamma.

Spec Sheet E-AB-27001 (PDF File)

Synonyms 4E BP1,4EBP1,BP 1,eIF4E binding protein 1,EIF4EBP1,PHAS I
Swiss-Prot Q13541
Concentration 1 mg/mL
Host Mouse
Immunogen Fusion protein of 4EBP1
Purification Method Protein A purification
Formulation PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Storage Store at -20?. Avoid freeze / thaw cycles.
Dilution WB 1:1000-1:10000, IHC 1:50-1:500, IF 1:20-1:200

Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .


* Remark Icon :

WB=Western Blotting, IP=Immunoprecipitation, IF=Immunofluorescence, IHC=Immunohistochemistory, IHC-p=Immunohistochemistory Paraffin, FCM=Flow Cytometry, CH=ChIP Assay

Manufactured by: Elabscience

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