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Active Caspase-3 Monoclonal Antibody

Price:
$69.00
SKU:
E-AB-22115-20
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Calculated at checkout

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Product Description

Product Name Cat# Clone# Isotype Applications Reactivity Unit/Size
Active Caspase-3 Monoclonal Antibody E-AB-22115 5A2 IgG WB,IHC-p* Human,Mouse,Rat20μL, 60μL, 120μL, 200μL

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

Spec Sheet E-AB-22115 (PDF File)

Synonyms Anti-Active Caspase-3
Swiss-Prot P42574
Concentration 1mg/mL
Host Mouse
Immunogen Recombinant Protein
Purification Method Protein A purification
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Storage Store at -20?. Avoid freeze / thaw cycles.
Dilution WB 1:500-1000, IHC 1:100-200

Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .

FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.

* Remark Icon :

WB=Western Blotting, IP=Immunoprecipitation, IF=Immunofluorescence, IHC=Immunohistochemistory, IHC-p=Immunohistochemistory Paraffin, FCM=Flow Cytometry, CH=ChIP Assay

Manufactured by: Elabscience

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