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ADRM1 Monoclonal Antibody

Price:
$185.00
SKU:
E-AB-27623-60
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Calculated at checkout

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Product Description

Product Name Cat# Clone# Isotype Applications Reactivity Unit/Size
ADRM1 Monoclonal Antibody E-AB-27623 1A1A3 IgG3 WB,ELISA* Human60μL, 120μL, 200μL

Description

The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.

Spec Sheet E-AB-27623 (PDF File)

Synonyms adhesion regulating molecule 1,ADRM1,ARM 1,ARM1,GP110,hRpn13,Rpn13,Rpn13 homolog
Swiss-Prot Q16186
Concentration 1 mg/mL
Host Mouse
Immunogen Fusion Protein of ADRM1
Purification Method Protein A purification
Formulation PBS with 0.1% sodium azide, 50% glycerol, PH7.3
Storage Store at -20?. Avoid freeze / thaw cycles.
Dilution WB 1:5000-1:20000

Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .

FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.

* Remark Icon :

WB=Western Blotting, IP=Immunoprecipitation, IF=Immunofluorescence, IHC=Immunohistochemistory, IHC-p=Immunohistochemistory Paraffin, FCM=Flow Cytometry, CH=ChIP Assay

Manufactured by: Elabscience

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