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Nuclear Receptors 

Nuclear hormone receptors are a family of 48 intracellular receptors that upon binding a lipid-soluble ligand move to the nucleus to function as transcriptional activators, associating with other general transcription factors, to regulate gene expression controlling various metabolic pathways. Malfunctions in nuclear hormone receptor signaling pathways caused by an individuals'habits leads to a variety of life-style related diseases, such as type II diabetes, obesity, hyperlipidemia, and circulatory disorders. Perseus Proteomics sells high quality antibodies to all 48 nuclear hormone receptors.

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