Product Description
In a collaboration with European Pharmaceutical company, we have developed a scaffold for culture of iPSCs for studying psychiatric disease. Neurons and astrocytes matured faster in 3D culture compared to conventional 2D culture and the co-cultures could be maintained for several weeks without affecting cell viability. First staining indicate that neurons develop a very dense neuronal network and surrounding astrocytes are in close interaction with them.
More functional readouts are currently being validated for the model.
Cells Tested:
iPSC, iNeuron
Specs:
Material: PCL
Stiffness: Medium
Porosity: Low
| Validated readouts | Analytical methods |
| Cell morphology | Confocal microscopy |
| Cell infiltration | Light-sheet microscopy |
Specification and Comparisons
| Breast Cancer platform | Pancreatic Cancer platform | Neuro iPSC platform | Neuro HNPC platform | |
| Porosity | High | Medium | Low | Medium |
| Stiffness | Low | Low | Medium | Medium |
| Material | PCL | PCL | PCL | PCL |
| Cells tested |
L929(mouse) and human fibroblasts MCF-10A |
AsPc1 CAFs |
iPSC, iNeuron |
neuronal progenitor cells (HNPCs)
|
| Reference |
Permlid et al, 2019 |
Case study | Case study |
Zalis, 2016 |
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by : Cellevate
|
Questions about this product? Email us at orders@iwai-chem.com or give us a call: (650) 486-1541 |
