In a collaboration with Swedish CRO, we have developed a scaffold for stable, long-term co-culture of pancreatic cancer and stromal cells. Their model for pancreatic cancer co-cultures, a traditional submerged 2D system had performance issues. Limited space meant contact inhibition was problematic and the system became over confluent around 4 DIV, which was not enough time to develop a disease relevant culture.
The model is currently being used to further investigate drug sensitivity and cytotoxicity.
|Validated readouts||Analytical methods|
|Cell morphology||Confocal microscopy|
|Cell infiltration||AlamarBlue® assay|
Specification and Comparisons
|Breast Cancer platform||Pancreatic Cancer platform||Neuro iPSC platform||Neuro HNPC platform|
L929(mouse) and human fibroblasts
neuronal progenitor cells (HNPCs)
Permlid et al, 2019
|Case study||Case study||
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by : Cellevate
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