BioMIMESYS® is an organ-specific Extracellular Matrix (ECM) formed by the crosslinking reaction of hydrosoluble modified hyaluronic acid (HA) and other ECM components (collagens, fibronectin, etc.) with ADH (Adipic acid dihydrazide), to create a "Hydroscaffold" 3D cell culture system.
•Hyaluronic acid (HA) + Collagen I & VI system, is a major component of the adipocyte extracellular matrix (ECM), where it plays an important role in connective tissue.
•HA-based scaffolds are formed by HA-grafted RGDS + Collagen I & VI system crosslinking HA with ADH to form reticulated chains.
•High molecular weight HA is made from Gram+bacteria, which makes it easily reproducible.
> Porosity: 120 ± 50μm
> Rheology: Young’s modulus: E= 0.45 ± 0.05kPa
> Swelling ratio = 60 ± 10g/g
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