Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Formulation: Supplied as a 0.2 μM filtered solution of PBS, pH 7.4.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Fusion Tag: N-6His
Expression System: E.coli
Mol Mass: 36.2kDa
Bio Activity: Immobilized Recombinant 2019-nCoV NP (Truncated)(Cat#DRA58) at 2μg/ml (100 μl/well) can bind Anti-2019-nCoV NP Antibody (6G9)(Cat#DA027), the ED50 for this effect is 4.8 ng/ml.
Synonyms: 2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by: Elabscience
Questions about this product? Ready to place an order? Email us at email@example.com or give us a call: (650) 486-1541