Recombinant Human Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Val333 is expressed with a 6His tag at the C-terminus.
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt; store it immediately at<-20 °C.
Fusion Tag: C-6His
Expression System: Human Cells
Mol Mass: 36.9 kDa
AP Mol Mass: 34 kDa
Synonyms: Cathepsin L1; Major Excreted Protein; MEP; CTSL1; CTSL
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by: Elabscience
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