Recombinant Mouse Cathepsin L/CTSL Protein His Tag) - Human Cells

Product Description

Recombinant Mouse Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Asn334 is expressed with a 6His tag at the C-terminus.

Background:
Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Shipping: Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

More Details:

Sequence: Thr18-Asn334
Fusion Tag: C-6His
Accession: P06797
Species: Mouse
Expression System: Human Cells
Mol Mass: 36.8 kDa
AP Mol Mass: 13-40 kDa

Synonyms: Cathepsin L1; Major excreted protein; p39 cysteine proteinase; Ctsl1;1190035F06Rik

Datasheet

FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Manufactured by: Elabscience