TGFβ1 inhibitor (TGFβ1 binding peptide)

Product Description

TGFβ1 inhibitor (TGFβ1 binding peptide)

Small kinase inhibitors are commonly used to inhibit the signaling of TGFβ-1, aiming to achieve cell differentiation. However, due to their lack of specificity, they can perturb other signaling pathways, leading to cytotoxicity. Unlike small kinase inhibitors, PG-002 does not exhibit inhibitory activity against Activin A, making it very specific to TGFβ-1 signaling.  PG-002 showed 100% inhibitory activity against TGFβ1 at 10 nM against 0.13 nM TGFβ1, which is equivalent to the commercially available neutralizing antibody.    

SKU:  PG-002
Formulation:  Lyophilized
Purity:  ≥95% (HPLC)
MW: 2587.90 (acetate)
Storage temp: ≤ -20°C
Size:  
10ug (eq. ~600ug of anti-TGFβ1)
100ug (eq. ~6000ug of anti-TGFβ1)

Product information sheet

Application Notes - Stability Test Results

FAQ

SDS

For Research Use Only

Manufactured by:  PeptiGrowth