Product Description
Product Name | Cat# | Clone# | Unit Size | Isotype | Applications | Reactivity |
Anti-Human TUPLE1 | BMR00669 | 374C6a | 100ug/ml (1ml) | IgG2a | DB,WB | Hu |
* Background
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.[NCBI Entrez Gene Summary]
*Quality of Control
Data Sheet BMR00669 (PDF File)
Western blot protocol (PDF File)
Antibody Concentration | 100 ug/ml (1.0 ml) |
Host Species | Mouse |
Preparation | This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
Sterility | Filtered through a 0.22 um membrane. |
Alternate Names | |
Accession No. | X75296 |
Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by : Bio Matrix Research, Inc.
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